DNA vaccines

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• DNA Vaccines, which are often referred to as the third-generation vaccines, use engineered DNA to induce an immunologic response in the host against bacteria, parasites, viruses, and potentially cancer.
• The basic working principle behind any DNA vaccine involves the use of a DNA plasmid that encodes for a protein that originated from the pathogen in which the vaccine will be targeted.
• Advantages over conventional vaccines: ease of production, stability, and transport at room temperature, decreased likelihood of replication interference as can been seen with live attenuated approaches.
• It is possible to vaccinate against multiple pathogens in a single vaccination

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